• Provides technical support for pilot- and commercial-scale production of intermediates and API that requires the application of innovative manufacturing technologies, especially for flow chemistry (i.e. continuous API production), preparative chromatography (HPLC, SFC, etc.), and micronization (dry and wet milling). Technical support are realized in the form of (include but are not limited to):
• Design, modification and assembly of equipment and set up
• Selection and evaluation of process technology and methods
• Development, determination and optimization of process parameters
• Devise tests before actual production, collect and analyze process data
• Enabling, execution and troubleshooting of production
• Serves as the subject matter expert or chief process engineer to communicate with clients and internal stakeholders to understand their technical requirements on API production. Translate such request into well-defined and practicable action items for the production team to implement. Report the production results afterwards, summarize key findings & problems, and suggest solutions for future improvement.
• Keep track of the status of existing manufacturing technologies that are already applied and identify areas of deficiency. Devise plans, action items and resources for technology consolidation, debottlenecking and continuous improvement.
• Explore, introduce and develop new technical capabilities and platforms based on project and market need by collaborating with R&D teams or other departments. Formulate long- term technical roadmaps to facilitate business growth and to create new source of revenue for the company.
• Supervise and mentor a team of subject matter experts and process engineers to ensure all the relevant API production projects are fully supported, and to build up a pipeline of versatile talents to meet the rapid growth in the service of the company.
• Manages a pool of specialized equipment and a number of laboratories and warehouses for flow chemistry, preparative chromatography and micronization. Adopt measures to maintain well-organized inventory, maximize equipment utilization rate and minimize the maintenance cost.
• Establish, develop and continuously upgrade the GMP documentation systems, standard operating procedures (SOP), technical working instruction (TWI) of various manufacturing technologies to ensure the production operation are compliant with the GMP policy and to satisfy the highest safety standard.
• Provides technical trainings and seminars to personnel of other departments to promote the application of new manufacturing technologies, and to resolve any misconception and miscommunication.

• Master, or more preferably, doctoral degree in chemical engineering, pharmaceutical engineering or other relevant disciplines
• 5+ years research or industrial experience in pharmaceutical, chemical or other related
• industries; oversea study research and working experience is definitely an advantage
• Familiar with API manufacturing process and jor common chemical unit operations
• Solid knowledge or experience in flow chemistry preparative chromatography and jor micronization is an advantage
• Familiar with GMP operation is preferred
• Good oral and written communication skill in English and Mandarin is a must

LOCATION

Jinshan, Shanghai City

CONTACT

Please send your resume to: elsa_li@wuxiapptec.com / wu_danjing@wuxiapptec.com