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Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Engineer - Pilot Plant

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will execute a variety of production and technology related projects in the Downstream (Purification) area of their large-scale pilot plant. The pilot plant delivers data and material to support process development of early and late stage clinical biologic molecules. The plant also prototypes and develops new technologies to support advancement of Amgen’s equipment and operations for current and future biologic facilities.

This Engineer will execute a variety of production-related operations in a large-scale facility, including but not limited to: performing processing on the floor (purification of Drug Substance); performing supporting activities such as buffer preparation, and equipment set-up/cleaning, and execution of downstream operations. Work will also include executing production runs, experiments, commercial program support, and characterization efforts. A significant amount of time will be spent performing ‘hands-on’ work in the plant. Additional activities will include defining & documenting operation practices, ensuring documentation accurately reflects operations performed, developing, and implementing area improvements (efficiency and safety) applying lean principles, commissioning equipment, and participating in operations meetings.

Engineering projects may include:

• Support new product introductions (wastewater assessments, process safety reviews)
• Technology development efforts (engineering assessments and equipment modifications)
• Functional and Site acceptance testing of new equipment
• Troubleshooting issues (root cause analysis) and leads continuous process improvements
• Support/Perform commissioning/qualification efforts
• Apply process engineering principles in design, specification, construction, startup and validation of process equipment and systems for projects of small to moderate scope and complexity

The Thousand Oaks Pilot Plant performs frequent piloting of novel process operations (focusing primarily on large molecule cell culture and purification operations), driving technology development, supporting innovation across Amgen’s entire spectrum, as well as executing non-GMP and pre-pivotal GMP bioprocessing operations for multiple mammalians and microbial Products, to develop & demonstrate production processes and produce bulk material. We produce sound, relevant data for the processes Amgen developments at meaningful scales that enable the rapid, successful transfer of our output to more dedicated manufacturing spaces. The environment is challenging, fast-paced and constantly evolving with varying degrees of process definition, but very rewarding for those that like hands-on science and want to make process improvements in a development space.

Must be able to work off hours or non-standard shifts.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The outstanding professional we seek is an engineer with these qualifications.

Basic Qualifications:

Master's Degree

Or

Bachelor's Degree & 2 years of Manufacturing, Scientific or Operations experience

Or

Associate's degree & 6 years of Manufacturing, Scientific or Operations experience

Or

High school diploma/GED & 8 years of Manufacturing, Scientific, Engineering or Operations experience

Preferred Qualifications

• Bachelor’s degree in Biological/Biochemical/Chemical Engineering, or other relevant field
• 3+ years of experience in process development, biotechnology manufacturing, or Life Sciences or Engineering fields
• Solid understanding of upstream/downstream operations
• General knowledge of the associated analytical and media/buffer preparation techniques
• Energetic and technically minded individuals, with strong interpersonal, leadership, and organizational skills
• Proven ability to learn new systems and applications, and various downstream techniques
• Proven ability to work effectively in team and/or project environments
• Strong math and digital literacy, as well as the ability to apply science-based thought processes to practical applications

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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