1. General job accountability:
Independently conduct laboratory experiments that include antibody library construction and sequence analysis, in vitro display (mainly on yeast), binding studies (i.e. FACS, ELISA)
Contribute protein engineering expertise to antigen design as well as to antibody format and sequence optimization engineering
Document protocols and foster sharing of expertise as a scientific resource for others in the organization
Strong organizational skills to ensure thorough information tracking in material management systems
2. Qualification and competency requirements:
A. Education/training background:
Master / PhD in (biochemistry, biology, immunology, or a related field)At least 1 year working experience in pharmaceutical or biotech companies is required
Understanding antibody structure and function is a plus
B. Knowledge/Skills:
Proficiency with molecular biology (PCR, plasmid construction, DNA sequence analysis)Proven knowledge and hands-on experience with at least one of the following:
Hybridoma, phage, yeast, or other panning technologyProtein chemistry, purification, binding studies (ELISA, FACS, BLI, BIAcore, etc.) or biochemical/biophysical and biological characterization
Transient and stable cell-line generation using lentiviral transduction and CRISPR
C. Others:
Good planning and execution skills to meet deadlines and to handle multi tasks
Quick learner and good team player
Strong problem-solving skills
职能类别: 医药技术研发人员
联系方式
上班地址:上海张江哈雷路866号
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