Associate Director/Director/Senior Director in Mammalian Production Cell Line Development
百济神州BeijingUpdate time: May 10,2019
Job Description
  • 招聘类型:社招
  • 工作性质:全职

职位描述

The Biologics Department of BeiGene R&D center in Beijing is seeking a highly motivated and experienced scientific team leader for the Mammalian Production Cell Line Development function. The selected candidate has a primary role in the generation and characterization of highly robust and productive stable CHO cell line suitable for biologics manufacturing. The selected candidate will be integral part of the Biologics CMC team to advance BeiGene’s increasing biologics products.

Job description:

  • Set up a highly efficient and robust platform for CHO production cell line development.
  • Design and optimize expression vector constructs.
  • Develop and characterize highly-productive stable CHO cell lines suitable for biotherapeutic manufacturing within project timelines.
  • Author and review technical reports detailing cell line development protocols and results. Effectively present scientific data and concepts to various audiences.
  • Maintain a high level of productivity in the lab, with clear and accurate documentation of experiments.
  • Contribute to team performance and process improvement in a climate of scientific excellence. Work collaboratively on projects across multiple cross functional teams.
  • Proactively seek out new information and opportunities to advance our technologies.

任职条件

Professional Requirements:

  • PhD. in cell biology, biochemistry and molecular biology, or related field with 3-5 years, or master degree with 8-15 years of relevant industrial experience.
  • Proven track record in one or more of the following: robust CHO cell line development, cell line genetic characterization, vector construction, cell line engineering such as gene knock-out/knock-in.
  • Understanding of the regulatory requirements for the production of therapeutic antibodies.
  • Thorough understanding and hands-on experience with mammalian cell expression systems.
  • Understanding of the pre-clinical drug discovery and clinical drug development phases.
  • Ability to work effectively in a highly collaborative and dynamic environment with cross functional teams.
  • Broad experience in biologics is required.
  • Experience with writing and reviewing development reports, SOPs, and batch records.
  • Ability to mentor and motivate teams to achieve high performance and practices.

职位要求

  • 学历要求:博士
  • 工作经验:无
  • 外语要求:English

公司福利

  • 五险一金 
  • 晋升空间 
  • 法定节假日

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