Associate Principal Scientist - HTS

Location:  Alderley Park with relocation to Cambridge, UK

Salary: Competitive with excellent benefits

At AstraZeneca, we turn ideas into life changing medicines. Working here means being results oriented, thinking big and working together to make the impossible a reality.

At AstraZeneca, we’re not afraid to do things differently. We’re building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening up new ways to work, pioneering cutting edge methods and bringing unexpected teams together.

We are looking to recruit a Principal Scientist or Associate Principal Scientist with expertise in biostatistics and/or image analysis computational methods with a focus on applying this experience to very large data sets to join our Global High Throughput Screening (HTS) Centre in Alderley Park, prior to relocation to a new, state-of-the-art R&D centre in Cambridge. HTS is the only department within our world-leading pharmaceutical business that focuses unequivocally on hit identification. This means you’ll get unrivalled exposure to the drug discovery process, working on multiple projects across therapeutic areas in a culture that fosters collaboration and open innovation – find out more at http://openinnovation.astrazeneca.com/

Our HTS centre aids the definition of screening cascades in discovery programmes, uses cutting-edge assay technologies to generate high-quality screening data and delivers robust data packages to pursue tractable hit series. If you are looking to share your experience, and get the training to build it, you could be leading and championing data interpretation as part of a team that uses world-class science and technology to deliver the most innovative tools for drug discovery.

What you'll do

As an experienced member of the High Throughput Screening department you will have specific accountability for developing statistical and computational methods to analyse HTS data sets to identify and extract the information to identify compounds of interest. You will be expected to champion the use of computational methods internally as well as represent HTS and AZ externally. You will also supporting scientific development of the department across all areas.

Essential Criteria

• Master’s degree in a relevant discipline
• Significant experience in the pharmaceutical industry and drug discovery process
• Well-developed understanding of molecular and cellular biology
• A proven track record in the application of computational and/or statistical methods to large biological data sets ideally in a drug discovery setting.
• Ability to drive the practical application of computational and/or statistical approaches to drug discovery.
• A history of scientific publication/presentation.

Location

This role will initially be based at  Alderley Park, Cheshire prior to the group relocating to Cambridge so you must be committed to moving with this role.

Desirable Criteria

• An advanced degree in a related field and/ or professional certification
• Ability to code in R
• Ability to code in a language such as Python
• Ability to query databases using SQL
• Excellent communication skills to facilitate knowledge transfer to HTS scientists
• Understanding of the analysis and interpretation of screening data

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being results-oriented - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, ground-breaking ground breaking methods and bringing unexpected teams together.

So, what’s next?

Are you already imagining yourself joining our team?

Are you ready to bring new insights and fresh thinking to this role?

Interested, then we would invite you to submit your application online by midnight on 13th Feb 2021.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.