Associate Scientist, Pharmacology II
AbbVieSouth san franciscoUpdate time: March 28,2022
Job Description
About AbbVie AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica, Venclexta, and Empliciti — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position is based at AbbVie’s new South San Francisco, CA location. We are seeking a highly motivated organized and skilled cell culture specialist to join the In Vivo Pharmacology group. The Scientist will conduct daily activities in our pharmacology Cell Culture Facility. You will be a member of a broader preclinical Pharmacology team. The in vivo pharmacology team conduct tumor efficacy and PK/PD studies, develop novel preclinical models and provide pharmacology support to innovative cancer drug development. Our team work collaboratively in a project team setting with biology, medicinal chemistry and DMPK scientists, providing in vivo proof-of-principle for target discovery and validation, formulating, and executing efficient in vivo structure activity relationship strategy and advancing oncology programs to clinical development. This position will report to an in vivo pharmacologist and work collaboratively in a project team setting. The core responsibility resides within Cell culture and will contribute to the progression of all in vivo studies. General Position Summary/Purpose: We are seeking an Associate Scientist II, cell culture leader to assist in the daily activities of operating and maintaining the Oncology Cell Culture Facility. This includes acquisition, maintenance, and propagation of human and mouse tumor cell cultures in support of the pharmacology team. The key responsibility will be the cryopreservation and organization of stocks, the organization of inventory, and maintenance of inventory database. The successful candidate should be able to learn the daily operation of the lab, rapidly adapt to changing project needs, independently plan and execute daily activities, and exhibit robust problem-solving skills. Excellent teamwork and communication skills as well as adherence to good documentation practices, and safety guidelines are essential. Qualifications Must have: BS/MS in biology, or related field with 3+ years of industry experience is preferred. Conduct daily cell line culture with aseptic technique to support in vivo studies. Both adherent and suspension cells will be involved. Cell culture cryopreservation and stock inventory. Cell line database maintenance. Proficient in general biology lab and tissue culture room routine maintenance. Detail oriented, Strong written and verbal communication skills, good record keeping and organization skills, and ability to multitask Strong teamwork mentality, respectful, good listener and eager to learn new skills Able to work independently and collaboratively on multiple projects in a fast-paced, dynamic environment. Nice to have: Experience with mammalian tissue culture, primary cell culture, tissue processing, and in vivo propagation of tumor cell lines. Genetic manipulation and sorting of cells to support efficacy studies and tumor model development. Standard molecular and cellular biology assays (Flow Cytometry, MSD, ELISA, Western blot, etc Significant Work Activities N/A Travel No Job Type Experienced Schedule Full-time Job Level Code IC Equal Employment Opportunity At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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