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Job Description

HOW MIGHT YOU DEFY IMAGINATION?

Do more with the knowledge you’re working hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Through this program, you will acquire the valuable hands-on skills and foundational experience to become the professional you are meant to be in your chosen field.

Grad Intern – R&D (Computational Biology Safety)

Live

This could be your everyday

Let’s do this. Let’s change the world. Amgen’s 2022 summer internship program offers meaningful project experiences that impact patient’s lives. For the internship program, we are seeking graduate students who are ready to make a positive impact and use their talents to accomplish more than they thought possible. Through these innovative projects, the graduate intern will not only make a timely impact in drug safety but will also obtain a holistic view of the entire circle of drug development, especially on what we do to ensure that the drugs we develop

are safe and that side effects are minimized or eliminated.

Off-target activity related adverse event is a main contributor to drug attrition and drug withdrawal during clinical development and post-marketing. With emerging therapeutic modalities, such as targeted protein degradation and RNA interference, rigorous off-target screening remains an unmet need to advance these new molecules. The Translational Safety & Bioanalytical Sciences group built a proteomics-based platform using human cell lines to address this issue. The graduate intern will help to continue building this platform using computational biology approaches and natural language processing methods developed by our group. The study scope includes the rational off-target selection from the entire human proteome using newest genetics and pharmacology evidence, as well as the algorithmic selection of the hosting cell lines (from ~1,100 human cells) using transcriptome data. The translatability of key organ toxicities will also be explored across species, using (pre)clinical evidence from various regulatory databases, which will guide the formation of organ-focused cell panels for our proteomics studies.

Win

Here’s what it takes to Win

We are all different, yet we all use our unique contributions to serve patients. The qualified individual we seek is a highly motivated person with these qualifications.

Basic Qualifications

Amgen requires that all individuals applying for a grad internship or a co-op assignment at Amgen must meet the following criteria:

18 years or older

Graduated with a Bachelor’s degree from an accredited college or university with a 3.0 minimum GPA or equivalent

Currently enrolled in an MBA program for an MBA internship OR a Master’s program for a Master’s internship OR a PharmD program for a PharmD internship OR PhD for a PhD internship from an accredited college or university and completion of the first year of MBA OR Master’s OR Pharm D OR PhD program before internship starts

Enrolled in an accredited college or university following the potential internship or co-op assignment

Must not be employed at the time the internship starts

Preferred Qualifications

Pursuing a PhD in Computational Biology or other relevant fields

In at least fourth year of PhD program by Fall 2022

Strong bioinformatics and cheminformatics background

Proficient programming in scripting languages including R and Python and/or programming languages (Java, C, C++)

Experiences with large data set

Structural biology and modeling a plus, but not required.

Ability to thrive in a high-performance culture

Excellent oral/written communication skills and interpersonal skills

Excellent time management, decision-making and organizational skills

Ability to apply research findings, capture information, interpret, and analyze results, develop and implement a logical and strategic plan of action

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

• Build a network of colleagues that will endure and grow throughout your time with us and beyond.
• Bring your authentic self to the table and become the professional you’re inspired to be through accepting culture that values diversity of thought and experience, and will flex to your strengths and possibilities.
• Participate in executive and social networking events, as well as community volunteer projects.

Apply now

for an internship that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com. Please search for Keyword 136695

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.