HTS Team Leader

Location:  Alderley Park with relocation to Cambridge, UK

Salary: Competitive with excellent benefits

At AstraZeneca, we’re not afraid to do things differently. We’re building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening up new ways to work, pioneering cutting edge methods and bringing unexpected teams together.

We are looking to recruit a Team Leader to join our Global High Throughput Screening (HTS) Centre. HTS is the only department within our world-leading pharmaceutical business that focuses unequivocally on Hit identification. This means you’ll get outstanding exposure to the drug discovery process, working on multiple projects across therapeutic areas in a culture that fosters teamwork and open innovation – find out more at http://openinnovation.astrazeneca.com/

Our HTS Centre aids the definition of screening cascades in discovery programmes, uses cutting-edge assay technologies to generate high-quality screening data and delivers robust data packages to pursue tractable hit series. Whether you’re looking to share your experience, or get the training to build it, you could be part of a team that uses world-class science and technology to deliver the most innovative tools for drug discovery.

What you'll do

As a Team Leader in the HTS department you will lead a team of scientists delivering High-throughput Screens to AstraZeneca drug projects and academic collaborators, maximizing individual talents and developing a high-performing team. You will have a passion for scientific delivery and innovation, developing science and technology strategy and shaping the future of the HTS capability, and building trusted relationships with senior scientific colleagues.

You will be a member of the Discovery Sciences organization, working within an outstanding scientific environment to support drug discovery across each of AstraZeneca’s Therapeutic Areas. You will develop and maintain a high level of science and technology knowledge, building specialist expertise in specific areas of drug discovery to lead your team effectively, providing mentorship, training and development. You will make an active contribution to the development of the HTS department through leadership of multi-disciplinary initiatives that deliver value and impact to drug discovery projects.

Essential Criteria

• BSc/PhD in a relevant biology discipline
• Proven experience in cell and/or biochemical screening approaches and ability to troubleshoot screening problems
• Ability to drive the practical application of new assay approaches to screening and drug discovery science in Hit Discovery
• Familiarity with technology-rich lab environments.

Location

This role will initially be based at Alderley Park, Cheshire prior to the group relocating to Cambridge so you must be committed to moving with this role.

Desirable Criteria

• Experience of leading a team in the delivery of high-throughput screens
• Experience of developing people to improve talent and ensure high performing teams
• Experience of leading a team in the identification, establishment and implementation of new technologies, methods, practices and ways of working.
• Experience in several cellular and biochemical screening technologies
• Assay Development, cascade design and drug discovery project team experience
• Phenotypic screening, imaging/flow cytometry, ion channel/GPCR experience
• Understanding of state-of-the-art assay and automation technology platforms
• Publication record and/or experience of presenting scientific data
• Strong understanding of the analysis and interpretation of screening data to understand mechanism of target engagement
• Experience of applying high volume/complexity data generation methods to drug discovery projects
• Experience of small molecule screening and/or fragment-based screening.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being results-oriented - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, ground-breaking ground breaking methods and bringing unexpected teams together.

So, what’s next?

If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us!

We invite you to submit your application online by midnight on 5th February 2021.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

29-Jan-2021

Closing Date

05-Feb-2021

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.