Immunogen/antibody structure analysis Scientist
和铂医药有限责任公司ShanghaiUpdate time: July 23,2019
Job Description
1. General job accountability:
  • Perform independently the immunogen/antibody structure analysis, including but not limited to the sequence alignment, X-ray structure superposition, mapping of mutation, and analysis of hydrogen bonding and hydrophobic interaction

  • Collaborate closely with other colleagues and deliver data in time



2. Qualification and competency requirements:


A. Education/training background:

  • MS or PhD in biochemistry or biophysics

  • At least two-year working experience in university, research institution, pharmaceutical or biotech companies is required





B. Knowledge/Skills:

  • Hands-on experiences in following fields are required

    • X-ray structural biology

    • Protein sequence alignment and 3D structure superposition using web servers or standalone programs

    • Handling PDB and FASTA files using text editor and web servers

    • Modelling using PyMol, Coot, UCSF Chimera or other programs

    • Analysis of hydrogen bonding and hydrophobic interaction using LigPlot

  • Ability to do simple Perl programming will be a great plus



职能类别: 医药技术研发人员

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