Lead Analytical Scientist (APS) – Highly experienced analytical scientist, On Market Support, Chemical Development
Location: Macclesfield
Competitive Salary & Benefits
Date Posted: 08.09.21
Make a more meaningful impact to patients’ lives around the globe
Here you’ll have the opportunity to make a meaningful difference to patients’ lives! With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and shaping the patient ecosystem.
Pharmaceutical Technology and Development (PT&D) are the bridge, which turns brilliant science into actual medicines that help millions of people. We work across the entire value chain, crafting and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.
We are currently recruiting for a Lead Analytical Scientist (APS), to join our multi-skilled On-Market support group within Chemical Development!
Chemical Development is dedicated to the lifecycle management of commercial active pharmaceutical ingredients (API) at AstraZeneca. Our drivers are to maintain continuity of supply, ensure license to operate and continue to deliver business value through optimisation of manufacturing processes and supply chain design. AstraZeneca currently manufactures a high percentage of API externally at Contract Manufacturing Organisations (CMOs).
What you’ll do
As a very experienced analytical scientist, you will be responsible for leading our analytical technical contribution to maintain and optimise supply for one or more AstraZeneca commercial products meeting cost, quality and environmental targets for our customers. This includes:
Leading the authoring and providing a significant contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product to global markets
Providing expert technical input to change control and improvement activities at CMOs and internal AZ API manufacturing sites, linking understanding to assess the impact of changes on control strategy and analytical measurements
Directing/influencing external organisations (CMOs) towards successful improvements of the manufacturing process including for example increasing process robustness and understanding, improving process efficiency, decreasing the analytical contribution to process variability and reducing environmental impact
Executing or providing support and technical direction for any technical/experimental work required during investigation and definition of corrective and preventative actions
Mentoring and developing junior colleagues, supporting them in reaching their full potential
Identifying and solving potential issues, and acting as an interface between departments
Contributing to the development of the On Market Strategy to support AZ current and future portfolio, defining, and delivering continuous improvement plans
All these activities will have a significant impact on the speed, quality, cost and environment impact of the AZ commercial portfolio, the overall success of the Supply Chain as well as ensuring the commercial viability and reducing carbon footprint of the medicine.
What you’ll need
BSc/PhD level education in a relevant discipline and a significant experience working within a Research & Development and Manufacturing environment, within the pharmaceutical industry
A good understanding of the overall drug development process from discovery through to launch
Experience of technical supervision, coaching and mentoring or leading small teams of people or scientific projects
A specialist in related analytical areas or techniques with the ability a to maintain that knowledge in order to provide expert advice
A thorough understanding of the principles and management of SHE and cGMP
Significant experience of delivering CMC content or contributions to regulatory filings throughout the life cycle of process or formulation analytical development, in the pharmaceutical industry
An understanding of key analytical techniques, including NMR, chromatography and mass spectrometry
Skills & Capabilities
Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement
Ability to analyse and interpret complex situations and provide clear strategic directions for others
Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally
Experience and skilled at facilitation at all levels
Proven problem solver with in depth technical skills
Demonstrates a high degree of personal credibility and end to end supply chain thinking
Proficiency in the use of statistics to understand data
The ability to expertly and optimally lead improvement projects
Experience of supporting commercial manufacture and working with contractors
Experience of late stage development with a background in an analytical skill group
With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.
What’s next?
Please note applications should include your current CV and cover letter which details your key areas of strength / development and why you should be considered for the role. We welcome your application by 21st September 2021.
Closing date: 21.09.21
Where can I find out more?
Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
Date Posted
08-Sep-2021Closing Date
21-Sep-2021AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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