About AbbVie AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. Since 2013, AbbVie has expanded its commitment to the San Francisco Bay Area, now represented by three facilities in Redwood City, South San Francisco, Sunnyvale and a future new Bay Area headquarters in South San Francisco. AbbVie employees in the Bay Area drive AbbVie’s research-based, innovation driven missions in healthcare. Specifically, Bay Area employees bring deep scientific expertise and commercial excellence to advance cancer care. Current oncology areas of focus include immuno-oncology, tumor targeting, tumor dependency and precision medicine. With facilities positioned in the heart of the biotechnology industry, we are able to collaborate with the best and brightest minds in oncology. AbbVie’s rapidly expanding Cell Therapy group is hiring a Principal Scientist II/Associate Director to guide the development of next generation cell therapies in the context of a highly innovative oncology pipeline. As a discipline expert and contact, the individual in this position will lead the generation of antigen-specific T and/or NK cell clones, designing and characterizing chimeric antigen receptor (CAR) constructs, and implementing CAR functional activity assessments. The individual is expected to drive functional performance by designing and implementing studies aimed at first- and best-in-class cell therapy products. Responsibilities: •Develops and achieves discipline strategy in alignment with functional goals and key scientific objectives. •Collaborates with experts within function to integrate scientific objectives into activities associated with development of new/improved products or technology. •Advances scientific expertise within function. Proactively advises and shares knowledge and expert opinions with subordinates, peers, and senior management. Mentors and trains functional colleagues and assesses current and emerging business challenges enabling functional goal achievement. •Ensures quality and effectiveness of key results of major project plans within function through sound design, early risk assessments, and implementation of fallback strategies. •Sources and identifies emerging scientific trends from multiple internal and external sources and assess relevance. Integrates trends into functional short-term objectives. Advances technology and direction within area of discipline. •Applies imagination and innovation by creating, inventing, and implementing new or better approaches, alternatives and breakthrough ideas that are valued by customers within the function. •Presents scientific concepts and results for functional scientific and non-scientific leaders as well as potential and existing partners. Maximizes impact and value of expertise. . Qualifications •Bachelor’s Degree in Science related field with 16 years of related work; Master’s Degree Science or PharmD with 14 years of related work; PhD in Science or related field with 8 years of related work experience. •Proven ability to innovate with a history of new or improved product releases. •Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators. . Extensive knowledge of T and/or NK cell biology research, including T cell receptors and oncology research is required. T and/or NK CAR cell therapy hands-on experience is a key advantage. Has expertise in cell and molecular biology research and/or viral transduction. Practical experience with several of the following techniques is required: primary cell culture, T cell-based assays and serial killing, flow cytometry, PCR (qPCR, ddPCR), ELISA, Luminex, retroviral/lentiviral/adeno-associated viral (AAV) transduction systems, T cell clone generation. Bioinformatics/data science capabilities (e.g. Spotfire, R-Studio) are an advantage. Significant Work Activities N/A Travel No Job Type Experienced Schedule Full-time Job Level Code M Equal Employment Opportunity At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.