Career Category

Research

Job Description

The Cardiometabolic Disorders (CMD) therapeutic area in Amgen Research is looking for a Principal Scientist (PS) who is trained as a physician-scientist in Cardiology or Endocrinology.

The PS will use fundamental biological insights to discover and develop drugs for cardiometabolic diseases.  The scope of work ranges from the earliest stages of scientific ideation to generation and characterization of drug candidates, with the final goal of delivering high quality molecules and programs for Amgen’s pipeline that are ready for human studies.  The primary focus will be on leveraging human data, cell/molecular biology, biochemistry, pharmacology, and preclinical models (both in vitro and in vivo) to build strong conviction around a therapeutic hypothesis, coupled with generation and testing of therapeutic molecules. The PS will also provide strong scientific support for programs that have entered clinical testing or have been approved.  As a physician-scientist, the PS will be expected to be a creative and rigorous investigator, as well as a broad, integrated thinker who will bridge communication between early discovery and all other functions at Amgen.    

Position Responsibilities

Work with a broad knowledge of human physiology/disease, clinical medicine, and basic biology to discover and develop drugs for cardiometabolic disease that will advance Amgen’s pipeline

Work in the laboratory independently as well as motivate, lead, and supervise the activities of others

Design, execute, interpret, and troubleshoot experiments

Present Research programs at cross-functional meetings

Communicate with colleagues in all other functions at Amgen, serving as an ambassador for Amgen Research

Enhance the external eminence of Amgen Research through high profile peer-reviewed publications, external presentations and relationships with academic institutions

Evaluate external opportunities for partnering or licensing new cardiometabolic assets

Basic Qualifications

Doctorate degree and 3 years of Scientific experience

OR

Master’s degree and 6 years of scientific experience

OR

Bachelor’s degree and 8 years of scientific experience

Preferred Qualifications

MD, MBBS or DO degree from an accredited medical school with formal training in laboratory-based basic biology, as evidenced by first or senior authored publications

Subspecialty board eligibility/certification in Cardiology or Endocrinology

Strong basic science background in academia or industry

If coming from academia, the candidate should be in a faculty position at an academic institution as a laboratory-based physician scientist

A record of high-quality peer-reviewed publications

Strong presentation and communication abilities (both written and oral)

Ability to anticipate problems and find creative solutions

Experience functioning as a discovery scientist and medical expert in a complex matrixed environment

A strong grasp of human biology and human genetics

Strong teamwork capabilities and leadership potential

 At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our “people-first” philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

Consistent with our core leadership value of “Develops the Best Team,” we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include:

• Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams
• Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities
• Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business
• Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement
• Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages
• Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission – to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.