Career Category

Research

Job Description

A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the promise of this emerging science to bring safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives.

The Clinical Biomarkers & Diagnostics department in Translational Medicine at Amgen is seeking a highly motivated Principal Scientist dedicated to clinical biomarker development in Oncology.

Integral to the ongoing success of Amgen’s comprehensive biomarker programs, the clinical biomarkers team is responsible for developing and executing the biomarker strategy for each program by applying cutting edge, innovative technologies to advance science in support of Amgen’s mission. The successful candidate is expected to work cross-functionally within Amgen and to interact closely with groups across both clinical development and discovery research.  The position will focus on the development and execution of translational biomarker strategies to inform pharmacodynamics, mechanism of action, and patient stratification/selection in support of the progression of Amgen’s pipeline candidates from late preclinical development through all stages of clinical development. The role is responsible for developing comprehensive biomarker strategies, designing experiments, authoring and implementing protocols, executing biomarker studies, organizing data, drafting technical reports or tech transfer documents, and interpreting and communicating results to cross-functional teams.

The role is expected to work in a highly matrixed environment and drive scientific and technical innovation collaboratively with other members of the Clinical Biomarkers & Diagnostics function, as well as with the Amgen research and development community.

Amgen employees adhere to all corporate and local guidelines and regulations related to compliance and health and safety.

Basic Qualifications

Doctorate degree and 3 years scientific experience

OR

Master’s degree and 6 years of scientific experience

OR

Bachelor's degree and 8 years scientific experience

Preferred Qualifications

PhD with 5+ years industry experience developing biomarker strategies in a clinical development setting and/or in preclinical biomarker discovery/validation

Knowledge and translational biomarker experience in immuno-oncology is highly desirable

Strong background in tumor biology and cancer genomics

Clinical development experience working with cross-functional teams conducting clinical trials

Experience in developing program-based strategies for pharmacodynamic, predictive, and exploratory biomarkers

Experience implementing a broad array of biomarker platforms and technologies to support clinical-stage programs

Demonstrated ability to establish and execute biomarker studies and collaborations with academic laboratories/KOLs

Experience in assay development and qualification and analysis of clinical samples

Experience managing biomarker assay outsourcing processes with external vendors and CROs

Poise and professionalism with strong communication and influencing skills in a dynamic environment

At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our “people-first” philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

Consistent with our core leadership value of “Develops the Best Team,” we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include:

• Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams
• Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities
• Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business
• Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement
• Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages
• Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans

A Fortune 150 company operating in nearly 100 countries around the world, we invest in highly skilled, dedicated and collaborative individuals who are ready to contribute to our mission in meaningful ways and make a difference in the lives of our patients. That’s why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Focused on the industry’s most compelling scientific discoveries and housed within industry leading facilities within the heart of the world’s leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.