Career Category

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

SCIENTIST – RNA Delivery Platform

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will be part of the fast-paced, integrated and interactive department of RNA Therapeutics with responsibilities including (but not limited to) the discovery, design, synthesis, and purification of novel compounds for potential clinical drug development. This will include the opportunity to work within Amgen’s RNA Platform Development group, which is focused on novel and innovative approaches to deliver RNA to modulate intractable targets in unmet medical conditions.

• The Scientist will work as part of the RNA Platform Development team responsible for developing RNA delivery strategies, including lipid nanoparticle (LNP) mediated delivery.
• The Scientist will design and optimize the LNP formulation and production processes.
• The Scientist will directly contact researchers within RNA therapeutics and multiple Therapeutic Areas to identify novel surface receptor ligands and lead efforts to utilize receptor ligands for functional delivery of oligonucleotides.
• Additional responsibilities include but not limited to: devising and implementing creative scientific strategies to address RNA delivery issues through conducting laboratory experiments, working closely with other researchers to influence team direction and advance programs, communicating progress and strategy in various forums, and preparing technical documents.
• The Scientist will serve as a scientific resource to the department who will champion new technologies/ideas to enhance capabilities.
• The Scientist may directly or indirectly lead research associates within a collaborative environment and be responsible for technical training and professional development.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The RNA Therapeutics professional we seek is a self-disciplined Scientist with these qualifications.

Basic qualifications

• Doctorate degree OR
• Master's degree and 3 years of LNP formulation experience or RNA chemistry or pharmaceutical research experience OR
• Bachelor's degree and 6 years of LNP formulation experience or RNA chemistry or pharmaceutical research experience

Preferred qualifications

• Doctorate degree in Organic/Medicinal Chemistry, Chemical Engineering, Biochemistry, Analytical Chemistry or a similar field
• Candidates should have a strong background in RNA delivery, especially in the extra-hepatic setting
• 3+ years of experience in LNP formulation or RNA chemistry or RNA delivery methods
• Experience in lab scale preparation of LNPs using microfluidics (Nanoassemblr)
• Proficient skills in isolation and analytical characterization of encapsulated LNPs
• Experience participating on a team that has advanced RNA-LNPs to clinical development
• Track record of consistent and successful drug discovery accomplishments (e.g., patent inventorship, conference presentations, and peer-reviewed publications)
• Deep understanding of drug discovery concepts with high lab productivity
• Demonstration of good lab practices, with particular attention to safety
• Experience coaching others (internal or CRO)
• Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and improve your potential along your career journey
• A diverse and expansive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.