Cell biology and immunology Scientists, leading our way into scientific breakthroughs

Location:  Cambridge, UK

Salary: Competitive with excellent benefits

Make a more meaningful impact to patients’ lives around the globe

Here you’ll have the opportunity to make a meaningful difference to patients’ lives. With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and shaping the patient ecosystem.

With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.

Be part of the team where you are empowered to follow the science

Have recently obtained your MSc or PhD and are looking for your next opportunity

Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs.

AstraZeneca is investing in Oncology cell therapy

AstraZeneca is a leader in Oncology with a global footprint and ability to deliver best in class medicines to the market. One area of significant investment within AstraZeneca is to become a leader in next generation cellular therapy products within Oncology. Through existing expertise in biopharmaceuticals, precise genome engineering and immunology across solid and haematologic malignancies, AstraZeneca is uniquely positioned to develop the best technologies for cellular therapies and is already growing a differentiated pipeline.

We are seeking  talented Scientists to join the Cell Biology and Immunology team with experience in at least one of the following areas: tumour immunology, immune cell biology, precise genome modification or cell therapy. This is an outstanding opportunity to join a fast-growing team within a vibrant environment focused on advancing oncology cell therapy through the generation and analysis of in-vitro cellular systems.

What you'll do

We are looking for talented scientists to join the team, these roles will be looking at enhancing the biology and activity of CAR-T cells using techniques such as CRISPR/genome editing, advanced cell models and immune assays.

We also have another fantastic role that will be focussed on advanced immune cell engineering technologies, using CRISPR, next generation sequencing technologies and omics analysis.

As part of an innovative team you will also be encouraged to contribute to the improvement of current cell engineering techniques - for use in cell therapies and as potential therapeutics. This role will interact across our global organisation and with high profile external collaborators. You will also have the opportunity to maintain scientific excellence, presenting data to key stakeholders internally and at external conferences, and publishing in peer-reviewed journals. Working within AstraZeneca’s Discovery Sciences unit, you will be joining a community of scientists with broad technological expertise dedicated to drug discovery.

We are looking for scientists with relevant knowledge in cancer cell therapy and a passion for science. At AstraZeneca we work together to provide medicines that make a real difference in patient care. A place with an ambitious and collaborative culture, where you'll feel valued and rewarded for your ideas and contributions.

Essential Criteria

• MSc or Ph.D in Immunology, Cancer Biology, Molecular biology, Cell Engineering, or equivalent experience
• Experience in one of the following areas: immune cells assay, cell models of human disease or gene editing techniques
• Strong experimental design and problem-solving skills
• Scientific excellence as shown by previous work, publication history and references from scientific mentors
• Excellent team working, communication and networking skills
• Experience of interacting optimally across disciplines, cultures and expertise.

Desirable Criteria

• Experience with viral delivery methods, flow cytometry, and/or omics analysis.
• Experience with CAR-Ts or primary immune cells
• Experience with Next Generation Sequencing (NGS) and/or genome editing off-target analysis.
• Practical understanding of cell and gene therapy product discovery and development.
• Experience in cellular, DNA and protein-based assays using a variety of technologies for measuring disease-relevant phenotypes
• Experience of working in external collaborations both in academia and pharmaceutical industry

Why AstraZeneca?

Make a more meaningful impact to patients’ lives around the globe

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Date Posted

20-Jul-2021

Closing Date

20-Jul-2021

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.