Job Title: Scientist III, Upstream Development
Work Location: Princeton, NJ
Division: Pharma Services Group (PSG)

At Thermo Fisher Scientific, each one of our 65,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

What Will You Do?
Designs and develops mammalian cell culture processes to support the production and manufacturing of recombinant proteins (including mAbs) under varying levels of direction, including, but not limited to cell culture scaleup, media development, harvest (recovery) process development, process range finding, and statistical analysis of data. Provides complex analyses in a biology environment by selecting appropriate methods with independent judgment. Develops scalable processes with improved product yield and reduced costs in a biologics environment. Collaborates with other areas of internal development and/or manufacturing operations.
 
Key Responsibilities:
 

• Performs media optimization, bioreactor process development, and cell culture clarification.
• Designs experimental plans based on the defined deliverables.
• Works with Process Development and Manufacture groups to trouble-shoot process challenges.
• Records results in notebook accurately, clearly, and regularly.
• Prepares protocols, reports, and test methods and writes SOPs.
• Maintains and ensures safe laboratory environment and work practices.
• Executes appropriately record and evaluates experimental data, including the writing and revising of process development reports and technology transfer protocols as needed.
• Remains current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences.
• Deep knowledge of varied aspects or a specialized aspect of discipline.
• Working knowledge of GMP/ GLP regulations in cGMP/ cGLP manufacturing environment. Excellent problem solving and critical thinking skills.
• Solid writing, communication and presentation skills.
• Strong MS Excel, PowerPoint and Word skills. Excellent organization and planning skills.
• Strong attention to detail and ability to adhere to standards procedures.
• Ability to design and execute tasks and studies based on the deliverables.
• Ability to analyze and summarize complex scientific data.
• Ability to create reports.
• Ability to function in a rapidly changing environment.
• Strong attention to detail and ability to adhere to standards procedures.
• Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.
• Ability to speak effectively before groups of customers and employees.
• Ability to make decisions that require choosing between limited alternatives to resolve complex problems. Ability to perform all required process steps.
• Ability to apply complex mathematical concepts to physical problems in areas.
• Ability to lead and mentor less experienced staff.

• Bachelor's degree or Master’s degree or PhD in biology, chemistry, biochemistry, chemical engineering, or a related field.
• With Bachelor’s degree, minimum of 5 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory.
• Relevant industry and discipline experience preferred.
• Experience using advanced statistical software packages and experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred
• With Master’s degree, 3 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory.
• Relevant industry experience and discipline preferred.
• Experience using advanced statistical software packages and experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred.
• With PhD, experience with practical scientific application necessary, though related experience not necessary.

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.