Career Category

Scientific

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will contribute to Amgen’s diverse discovery and development portfolio of therapeutic modalities with a focus on understanding the pharmacokinetics and pharmacodynamic properties of small and large molecule drug candidates being developed across multiple therapeutic areas in Amgen’s pipeline.

This role will be responsible for supporting PKPD-related and mathematical modeling activities in the PKDM space for drug discovery and development. The Scientist in this role will work directly with other PKDM partners to apply quantitative solutions in the development of novel therapeutics through various activities including target/compound evaluation, design of preclinical studies, investigation of exposure-response relationships, execution of translational strategies, and influencing clinical study design.

In this position, the core responsibilities include:

• Devise and implement quantitative analysis and strategies to inform decision making in drug development by using mathematical modeling and quantitative pharmacology principles with a focus on mechanistic and translational modeling.

• Serve as a functional representative and subject matter expert on PBPK modeling of small molecule therapeutics and collaborate with scientists across our PKDM scientific community

• Conduct hands-on work on fit-for-purpose mathematical models (PK-PD, PBPK) using specialized relevant modeling tools

• Present data in department and team meetings and contribute to external presentations including posters and manuscripts

• Summarize and articulate salient findings, communicate conclusions back to project team representatives and cross-functional teams and actively participate in team discussions supporting decision making in drug development

• Build effective collaborations with peers and partners within and outside the PKDM department including chemistry, biology, toxicology, biomarkers and protein scientists

• This position also provides the opportunity to pursue scientific inquiries into PK/PD relationship of small and large molecule bio therapeutics, authoring of scientific reports, scientific papers and presentations at scientific meetings.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Scientist with these qualifications.

Basic Qualifications:

• Doctorate degree OR

• Master’s degree and 4experience in drug discovery and development OR

• Bachelor’s degree and 6 years of Scientific experience

Preferred Qualifications

• Doctorate (Ph.D.) in chemical or biomedical engineering; applied mathematics; quantitative pharmaceutical sciences or a related field with 5+ years of experience in drug discovery and development

• Hands-on experience using Phoenix/WinNonlin, ADAPT, SimBiology/MATLAB, R, or relevant modeling software is required

• Must have strong understanding of pharmacokinetic and pharmacodynamic principles

• Ability to deliver on timelines and adapt to rapid changes in project priorities.

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and increase your potential along your career journey

• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

• Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.