Career Category

Research

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Scientist, PKDM, Small Molecule, ADME

Live

What you will do

Let’s do this. Let’s change the world. . In this vital role you will design and implement in vitro and in vivo mechanistic studies in support of small molecule discovery research and clinical development.

The department of pharmacokinetics and drug metabolism (PKDM) within Amgen is dedicated to the discovery and development of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion (ADME) and pharmacokinetic properties of novel therapeutic drug candidates to improve their pharmacological potential.

Specific responsibilities include but are not limited to:

• Support in vitro and in vivo small molecule ADME characterization as well as pharmacokinetic and pharmacodynamic analysis.

• Develop and employ LC-MS-based bioanalytical methods for the quantitative and qualitative analysis of small molecules.

• Interpret and communicate research results to PKDM project team representatives in support of drug discovery and clinical development.

• Instrument maintenance and troubleshooting, electronic laboratory notebook keeping, and communication of results to cross-functional project teams.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The PKDM Scientist we seek is a professional with these qualifications.

Basic qualifications:

Doctorate degree

OR

Master’s degree and 4 years of analysis of small molecules

Or

Bachelor’s degree and 6 years of experience mentioned above

Beyond that, additional Preferred Qualifications are:

• Strong background preferred in the use of biophysical, biochemical, and cell-based analytical methods to interrogate molecular attributes, including drug-target interactions that potentially influence their plasma pharmacokinetics and tissue distribution.

• Experience with molecular pharmacology techniques, primary hepatocyte cell culture, and in vivo PK models is highly desired.

• Experience with operation, troubleshooting, and data interpretation of LC-MS is required.

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

• Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.