Scientist - Predictive Pharmacokinetic Modelling
AmgenCanada - calgaryUpdate time: October 27,2021
Job Description

Career Category

Scientific

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Scientist - Predictive Pharmacokinetic Modelling

Successful candidates must reside in the Greater Vancouver area

Live

What you will do

Let’s do this. Let’s change the world.

We are looking for a Scientist with experience in predictive pharmacokinetic (PK) modelling to understand the in vivo behaviour of early drug candidates against diverse targets with the purpose of helping to design better molecules for human therapy. This is a permanent role that offer potential for advancement and career development.

In this vital role you will work with a multidisciplinary team to develop antibody dose and exposure-response relationships for multiple programs and use this information to help establish antibody affinity and potency design goals through in silico pharmacokinetic modelling. This modelling will have inherent assumptions, so the candidate will have the opportunity to perform pre-clinical experiments to help refine these assumptions through the biological or biophysical characterization of the therapeutic targets or antibody panels. Well-suited applicants will have a solid understanding of the PK principles and modelling, as well as a familiarity with modelling software. You should have a passion for tackling difficult research challenges and a positive approach to working in a team-based research environment.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a passionate individual with these qualifications:

Basic Qualifications

Doctorate degree in life sciences, pharmaceutical sciences or related field

OR

Master’s Degree and 4 years of scientific experience

OR

Bachelor’s degree and 6 years of scientific experience

Preferred Qualifications

  • Familiarity with the principles of pharmacokinetics and pharmacodynamics

  • Working experience with PK modelling to determine antibody design goals

  • Familiarity with modelling software and programming to optimize target-specific pharmacokinetic modelling

  • Experience in bioassay and biophysical / affinity screening for the identification of therapeutic antibodies

  • Capacity to identify, evaluate, implement and become proficient in novel laboratory techniques

  • Proven initiative, teamwork, collaboration and passion for developing technical expertise from assay development to routine execution

  • Highly organized and motivated self-starter with outstanding problem-solving skills

  • Outstanding oral and written communication abilities
     

Thrive

Some of the vast rewards of working here
 

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

www.amgen.ca/career

Amgen endeavours to make its recruitment process accessible to any and all users. Reasonable accommodations will be provided, upon request, to applicants with disabilities in order to facilitate equal opportunity throughout the recruitment and selection process. Please contact TalentAcquisitionInquiries@amgen.com to make a request and ensure you include the requisition number.

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