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Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Scientist – Structural Biologist - Induced Proximity Platform

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will be a part of Amgen’s Induced Proximity Platform (IPP). The IPP is charged with developing Amgen’s newest drug modality aimed at Targeted Protein Degradation, including discovery of PROTACs and molecular GLUEs. The IPP takes innovative, cross-discipline approaches, including targeted protein degradation, to tackle the toughest targets. The IPP is seeking a creative, emerging scientific leader to discover and develop novel therapies for cancer and other therapeutic areas.

• Lead a project to support discovery and development of novel therapeutic modalities based on Targeted Protein Degradation.
• Work closely with the Structural Biology program and be responsible for structure determination of target molecules using cryo-electron microscopy and X-ray crystallography. The candidate will be working closely with molecular biologists and protein biochemists in the protein expression group.
• Interact directly with both small molecule and large molecule scientists including computational scientists, medicinal chemists, and protein engineers.
• Flexible to apply her/his knowledge to new areas of study, thrive in a highly collaborative environment with strong interpersonal and communication skills.
• Inform departmental goals and strategy and will represent the department in various cross-functional activities including academic collaborations, external research evaluations, project teams, and scientific committees.
• Set project goals and timelines, design, perform and analyze experiments, interact with team members across different departments and research sites, and communicate and present data to department leadership.
• Expected to contribute to the scientific community through conference presentations and impactful publications.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientific professional we seek is an emerging leader with these qualifications.

Basic Qualifications

Doctorate degree OR

Master’s degree and 4 years of Structural Biology experience

Preferred Qualifications

• Ph.D in Structural Biology
• Postdoc research experience in large macromolecular complexes and/or membrane proteins.
• Experience in single particle cryo-EM workflow including grid freezing and screening, data collection and processing, three-dimensional reconstruction and model building.
• Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, crystallization, structure determination and analysis.
• Excellent presentation skills (written and oral) for effective team-based communication of results.
• Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.
• Skills in managing multiple projects and capability to prioritize.

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.