Career Category

Scientific

Job Description

Amgen is seeking a hands-on dynamic molecular pathology Senior Associate Scientist to work in the Department of Comparative Biology and Safety Sciences (CBSS) at our South San Francisco, CA location.  The Senior Associate Scientist will help develop and implement specialized tissue-based assays (including multiplex assays and image analysis) to support specific portfolio related questions on target expression and preclinical model development.  Responsibilities include:

• Development and implementation of histopathology assays including single and multiplex immunohistochemistry (IHC) assays, in situ hybridization (ISH), both colorimetric and immunofluorescent, and use a variety of imaging modalities.
• Assist with developing image analysis algorithms and performing analysis on studies.
• Collaborate with Pathologists, Scientists and Research Associates on multiple concurrent projects to evaluate and deliver data, contribute to early programs and assist with determining mechanism of action and toxicity.
• Work as part of a cross functional team to provide tissue-based assay development for target qualification, pharmacodynamic and efficacy readouts, and biomarker development.

Basic Qualifications

Master’s degree and 3 years scientific experience

OR

Bachelor's degree and 5 years scientific experience

Preferred Qualifications

• Bachelors or masters degree in molecular biology, cellular biology or related discipline with six or more years’ experience in molecular pathology in an industry setting.
• Significant hands-on experience in a variety of pathology-based methodologies including: IHC, multiplex IHC, ISH, laser capture microdissection (LCM), immunofluorescence imaging, confocal microscopy and other advanced microscopy, digital pathology/image analysis, stereology, specialized tissue sectioning and histology procedures.
• Expertise in documentation, analysis, interpretation and presentation of data generated from tissue-based target expression experiments with a variety of statistical approaches.
• Experience in successful representation of pathology projects at cross-functional team meetings.
• Comfortable working in a dynamic environment designed to promote frequent interaction and brainstorming.
• Ability to manage multiple projects simultaneously.
• Excellent communication skills.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.