Job Title: Senior Design Engineer / Single Use Technologies
Requisition ID: 113732BR
 
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. Our global team of more than 75,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon. For more information, please visit www.thermofisher.com. 
 
Location/Division Specific Information
 
St Louis, MO | BioProduction Division
 
 
How will you make an impact?
 

• Provides leadership in implementation of Upstream and Downstream based collaboration projects across both Thermo Fisher and PSG as a member of the Bioprocessing Collaboration Team (BCC). Acts as lead on multiple programs. Investigates, creates, and develops new scientific methodologies on a SUT unit operations in a cross company matrixed team environment. Evaluates and contributes to the discovery, development and innovation of Single Use Technology unit operations and supporting systems (including automation execution).
• Tests bioreactors, develops harvest technologies, supports continuous processing strategies. Drives early adoption of new SUT’s into both clinical and commercial operations at both PSG internally to Thermo Fisher as well as aids in the launch strategies for new SUT’s at Thermo Fisher.
• Drives the design of new technology processes and supports problem solving as necessary with independent judgment. Able to solve complex problems with regards to Cell Culture opportunities in industry. Determines methods and procedures including automation support to new assignments and may coordinate activities of other employees and or cross functional business teams. Supports implementation of the following technologies: Analytical benchtop equipment, SUT cell culture systems, Automation application to cell culture control and data trending.
• Tests and Develops Upstream, Downstream, Media and Buffer SUT applications, develops harvest technologies, supports downstream continuous processing strategies. Drives early adoption of new SUT’s into both clinical and commercial operations at both PSG internally to Thermo Fisher as well as aids in the launch strategies for new SUT’s.

• Drives the design of new technology processes and supports problem solving as necessary with independent judgment. Able to solve complex problems with regards to Protein Purification opportunities in industry (across Thermo Fisher Development and Patheon Operations). Determines methods and procedures including automation at the analytical bench scale as well full-scale purification scale. May coordinate activities of other employees and or cross functional business teams. Supports implementation of the following technologies: Analytical benchtop equipment, SUT downstream systems, Automation application to purification control and data trending. Will aid in project management for development of key projects within the Bioprocessing Collaboration Center at St Louis
• Leads design of experimental plans based on the defined deliverables.
• Conducts complex analyses to support testing and development of SUT systems. Works with Process Development and Manufacturing groups to trouble-shoot process challenges.
• Records results in notebook accurately, clearly, and regularly, and reviews documentation by others.
• Prepares protocols, reports, and test methods and writes SOPs. 
• Cell Culture/ Purification:  Has good understanding of SUT equipment supporting both upstream and downstream applications – including media prep and buffer prep unit operations and support.
• Aids in the development of cell culture and protein purification processes which can be scaled up for protein production and facilitates the Technology Transfer to Downstream Manufacturing groups globally

• With Bachelor’s degree, minimum of 8-10 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory and that includes relevant industry and discipline experience.
• With Master’s degree, 4-6 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory that includes at least 4 years of relevant industry discipline experience.
• With PhD, significant practical scientific application directly related to job responsibilities; that includes at least 4 years of relevant industry discipline experience related industry and discipline experience preferred.

• Advanced and deep knowledge of varied aspects or a specialized aspect of Single Use Technologies and working knowledge of principles and concepts in other relevant disciplines.  Strong knowledge of general cGLP procedures and those specific to discipline. 
• Strong knowledge of GMP/ GLP regulations in cGMP/ cGLP manufacturing environment. 
• Ability to design complex studies based on the deliverables. 
• Ability to analyze and summarize complex scientific data.  Ability to author reports, procedures, and other documents.  Ability to function in a rapidly changing cross company matrixed environment.  Strong attention to detail and ability to adhere to standards procedures. 

 
At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.
 
Apply today! http://jobs.thermofisher.com
 
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.