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Job Description

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

Live

What you will do

What we expect of you

Let’s do this. Let’s change the world. The key role of Senior Principal Scientist will encompass preclinical efforts to diversify and support Amgen's large molecule immunotherapy portfolio with an emphasis on Amgen's T cell engager platforms (BiTE® and UniDabs) and approaches to enhance the durability and depth of response to T cell engager therapy in patients. The ideal candidate will have a track record of innovative discovery biology supported by presentations, publications, or patents with a strong drive and experience in advancing therapeutic candidates in Oncology or Immuno-Oncology.

In this role, your core responsibilities are to:

• Drive the progression of small molecule discovery and development teams as a PKDM project team representative; experience with inhaled therapeutics is preferred

• Lead PKDM efforts for IND and NDA filings

• Interact with partner contract research organizations (CROs) to develop and implement novel small molecule in vitro assays and support project progression

• Evaluate and implement novel technologies to characterize the metabolism and disposition of new chemical entities

• Build close relationships with partner functions and therapeutic areas

The ideal candidate will have a proven track record of project team support, building teams with partner CROs, and strong external eminence (publishing). This role requires an excellent understanding of preclinical ADME and the factors influencing drug disposition, as well as an individual that can work collaboratively in a highly matrixed environment.

In addition to the core responsibilities, the position provides the opportunity to pursue scientific inquiries into the fundamental physiological and biochemical factors that determine the absorption, distribution, and clearance of protein and other emerging therapeutics. A collaborative and highly capable scientific community at Amgen is available to support these efforts. Interactions and collaboration with academic and other external scientists is highly encouraged

Win

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of related experience

Or

Master’s degree and 5 years of related experience

Or

Bachelor’s degree and 7 years of related experience

Thrive

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

• Vast opportunities to learn and move up and across our global organization

• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us. careers.amgen.com

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.