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HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

Senior Scientist - Analytical

Live

What you will do

Let’s do this. Let’s change the world. Amgen is a leading biotechnology company with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses.

Amgen’s Attribute Sciences (AS) department within the Process Development (PD) organization defines the favorable quality characteristics of the therapies it produces and optimizes innovative analytical tools to guide that development. The Pivotal PD organizations focus is developing and commercializing robust manufacturing processes across a wide range of therapeutic modalities, including (but not limited to) synthetic medicines, monoclonal and bispecific antibodies, bispecific T-cell engagers (“BiTEs”), and live oncolytic viruses.

Located at our Thousand Oaks, CA office the PD Senior Scientist will be responsible for the analytical development for therapeutic proteins in the pivotal and commercial stages.

Key responsibilities:

• Support drug substance and drug product process development, collect analytical data and participate in technology transfer activities
• Develop the LC-MS based Multi-Attribute Method (MAM) for late stage and commercial molecules
• Validate and transfer MAM to QC network
• Communicate (verbal and in written) scientific concepts and results
• Work collaboratively with other scientists on multidisciplinary teams
• Work independently in advancing projects and studies within required deadlines.
• Author technical reports

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications.

Basic Qualifications:

• Doctorate degree and 2 years in Analytical chemistry, Biochemistry or equivalent experience OR
• Master’s degree and 5 years in Analytical chemistry, Biochemistry or equivalent experience
• Bachelor’s degree and 7 year in Analytical chemistry, Biochemistry or equivalent experience

Preferred Qualifications:

• Ph.D. in Analytical Chemistry, biochemistry, chemistry, chemical engineering or other life science area with extensive mass spectrometry training
• Two or more years in the pharmaceutical or biotech industry in process and product development and drug substance and drug product analytical method development
• Strong lab skills to design and complete scientific experiments, interpretation of complex data and deliver results
• Strong background on LC-MS analysis of product quality attributes associated with therapeutic proteins (such as glycosylation, deamidation, oxidation, partial reduction etc.)
• Strong expertise in analytical method development, qualification, and troubleshooting HPLC/UPLC and mass spectrometers
• Solid understanding of Good Manufacturing Practices (GMP) requirements and their application in a phase appropriate manner
• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
• Strong problem solving and effective multi-functional interpersonal skills

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

• Vast opportunities to learn and move up and across our global organization
• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

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