Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals, and branded generic medicines. Our 109,000 colleagues serve people in more than 160 countries.

Sr. Scientist – Research Mass Spectrometry Group

Location: Abbott Park / Lake Bluff, IL  

ABOUT ABBOTT DIAGNOSTICS:

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 109,000 colleagues serve people in more than 160 countries.

Our location in Abbott Park (Lake Bluff), IL  currently has an opportunity for a Sr. Scientist – Research Mass Spectrometry Group

WHAT YOU’LL DO

Primary Job Function:

The primary function of this laboratory position is the design and execution of protein mass spectrometry experiments using multiple techniques towards the characterization of biologics used in clinical immunoassay formulations.

Core Job Duties:

The successful candidate must be capable of skillfully and independently conducting multiple mass spectrometry (MS) techniques primarily applied to proteins and other biomolecules. A specific requirement of the dedicated mass spectrometrist position includes expertise with structural characterization and MS method development of a variety of proteins (recombinant proteins, monoclonal antibodies, peptides, etc.).  A further requirement includes expertise in identifying host cell proteins from a variety of cell lines (E. Coli, CHO, etc.).

The candidate must be capable of functioning within a cross-functional team involved with new immunoassay product development and able to anticipate critical assay development needs from analysis of target biologic(s).  Ability to critically process analytical data and results with attention to detail is a necessity. Further skill will be required for interpretation and summarization of data from an array of analytical methods for diverse stakeholders, as well as design follow-up experiments where applicable. The position will require excellent team-working and adaptability competencies as well as strong technical communication skills, both in written and oral form.  The candidate must also be effective with timely and accurate record-keeping and communication of laboratory work.

Special Work Activities and Conditions:

Continuous sitting and standing for prolonged periods (more than 2 consecutive hours in an 8 our day). Keyboard use expected to be greater than or equal to 50% of the workday. Will also routinely work with laboratory chemicals and reagents.

Backup / Additional Description:

Performs research laboratory functions involving the design and execution of MS experiments toward characterization of biologics used in clinical immunoassay formulations.  A specific requirement of the position includes demonstrated expertise with multiple MS methods and instruments.  Responsible for compliance with applicable Corporate and Divisional Policies and procedures.  Must be capable of functioning within a cross-functional team involved with new product development and able to anticipate critical needs from analysis of target biologic(s).  Ability to critically process analytical data and results as well as interpretation and summarization of data from analytical methods for stakeholders is a necessity. Excellent team-working and adaptability competencies as well as strong technical communication skills, both in written and oral form.  Must be effective with timely, accurate record-keeping of laboratory work. Degree(s) should be in either a biological or chemical science field.

EDUCATION AND EXPERIENCE YOU’LL BRING

PREFERRED / IDEAL:

Educational Requirements:

Ph.D. with at least 2 years relevant research or industrial experience as noted below or MS with at least 4 years relevant research or industrial protein mass spectrometry experience as noted below or BS with at least 6 years relevant research or industrial protein mass spectrometry experience as noted below.

Experience:

Proven experience with standard mass spectrometry (MS) methods used to characterize proteins and other biomolecules is required.  Past demonstration of an ability to optimize MS methods to new applications and troubleshoot instrumentation or method problems when they occur is also a requirement. Structural characterization by MS including molecular weight profiling & peptide mapping, mapping of post-translational modifications, epitope mapping, lot-to-lot protein comparison and glycan analysis of glycoproteins.  Identification of host cell proteins from a variety of cell lines is crucial.  MS method development including use of ESI-MS and MALDI-TOF instruments for the above characterization as well as site(s) of conjugation/glycosylation and glyco profiling/carbohydrate structure determination.  Protein de novo, top-down, and middle-down sequencing experience by MS is not required but would be helpful. Knowledge of test method characterization and/or validation processes, as well as execution of MS methods under established operating procedures would be beneficial.

Minimum Requirements:

• Ph.D. in a life or physical science preferred with up to two years research or industrial

experience or BS/MS degree with additional progressive research experience sufficient to

demonstrate equivalency.

• Experience with presenting results of projects both internally & externally.
• Present complex technical data to large and diverse groups.
• Ability to train others on the theoretical and practical basis of techniques, processes and

assays.

• Familiar with project planning, process updates, & experimental design Prepares & align

impact goals with department goals.

WHAT WE OFFER

At Abbott, you can have a good job that can grow into a great career. We offer:

• Training and career development, with onboarding programs for new employees and tuition assistance
• Financial security through competitive compensation, incentives and retirement plans
• Health care and well-being programs including medical, dental, vision, wellness and occupational health programs
• Paid time off
• 401(k) retirement savings with a generous company match
• Pension Plan
• The stability of a company with a record of strong financial performance and history of being actively involved in local communities

Learn more about our benefits that add real value to your life to help you live fully:  www.abbottbenefits.com

Follow your career aspirations to Abbott for diverse opportunities with a company that provides the growth and strength to build your future. Abbott is an Equal Opportunity Employer, committed to employee diversity.

Connect with us at www.abbott.com, on LinkedIn at www.linkedin.com/company/abbott-/, on Facebook at http://www.facebook.com/Abbott and on Twitter @AbbottNews.

JG: 17

JCC: RD/DV/PROF2/17033/053