We are currently looking for scientists with excellent laboratory skills to join the Bioscience COPD/IPF team within the Early Respiratory & Immunology Department, based in Cambridge, UK .

Main Duties and Responsibilities

As part of the team you will execute in vitro experiments as well as support analysis from both in vitro and in vivo studies to progress our drug discovery projects and publishable scientific insights. You are encouraged to actively take part in scientific discussion to add valuable input in experiment design and data interpretation to drive projects and techniques.

This is a lab-based role where you will be involved in multiple ongoing projects with responsibility to analyse samples from experiments from various cells and tissues for both in vitro-, in vivo- and patient studies. We are looking for someone with experience in culturing of primary cells, immunohistochemistry, immunoassays, protein and RNA analysis.

Accountabilities:

• To be an effective team member in supporting drug discovery projects to meet their objectives
• To conduct where appropriate in parallel more than one area of work to agreed timelines
• Can interpret experimental data and play a significant role in the planning of further experiments
• Can contribute to writing peer-reviewed publications, abstracts and patents
• Responsible for ensuring that their scientific knowledge influences project progression in accordance with portfolio priorities

Essential Requirements

• A PhD or BSc/MSc with relevant experimental experience  
• Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude.
• Highly organized and self-motivated, with a proven ability as a strong team player
• Excellent English is required, with both strong verbal and written communication skills
• Strong hands-on experience with primary cell culture

The following skills are desirable

• Experience in the use of immunological, pharmacological, cellular or molecular methods (in vitro, ex vivo) relevant to the study of respiratory disease (for example, ELISA, immunofluorescence, immunohistochemistry, western blotting, molecular biology, gene editing, imaging and image analysis)
• Experience working with human lung epithelial cells, fibroblasts and/or iPS cells
• An understanding of Respiratory Diseases such as COPD or IPF

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.